| 释义 |
properdin Phys.|prəʊˈpɜːdɪn|
[f. L. prō- pro-1 + perd-ere to destroy (see perdition) + -in1.]
A protein found in the blood and concerned with the body's response to infection.
1954Science 20 Aug. 279/1 This protein, tentatively named properdin.., acts only in conjunction with complement and Mg+ + and participates in such diverse activities as the destruction of bacteria, the neutralization of viruses, and the lysis of certain red cells. Properdin is a normal serum constituent and differs from antibody in many respects, particularly in its lack of specificity and in its exact requirements for its interactions. [Note] Hans Hirschmann..suggested this name. 1963C. J. C. Britton Whitby & Britton's Disorders of Blood (ed. 9) xiv. 356 Properdin levels are low in acute leukæmia. 1975Spragg & Gigli in Mathieu & Kahan Immunol. Aspects Anesthetic & Surg. Pract. vi. 116 Properdin has been highly purified as a distinct protein with a molecular weight of 223,000 daltons. |