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单词 naltrexone
释义 naltrexone, n. Pharm.|nælˈtrɛksəʊn|
[f. as naloxone n. with arbitrary element -tre-.]
A narcotic antagonist, C20H23NO4 , related to nalorphine and naloxone but usually given orally as the hydrochloride.
1973Arch. Gen. Psychiatry XXVIII. 785/2 Naltrexone is approximately 17 times more potent than nalorphine in precipitating abstinence in patients dependent on 60 mg of morphine a day.1978Nature 9 Mar. 167/1 This treatment is designed to diminish the efficacy of any self-administered opiate by ‘blockading’ the receptors with substances such as naloxone or naltrexone.1988New Scientist 9 June 83/3 A similar bait has been advocated in order to ‘persuade’ heroin addicts to submit to a course of naltrexone, or to encourage criminal alcoholics to take the very nasty Antabuse.
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