ophthalm- bef. a vowel, = ophthalmo-: as in ‖ ophthalˈmalgiaPath.[Gr. ἄλγος pain], pain in the eye; neuralgia of the eye-ball; hence ophthalˈmalgica.‖ ophthalmaˈtrophia, ophthalˈmatrophyPath.[Gr. ἀτροϕία atrophy], atrophy of the eye-ball; shrivelling or wasting of the eye. 1892in Syd. Soc.Lex.