| 释义 |
oxygenase Biochem.|ˈɒksɪdʒəneɪz, -s|
[a. G. oxygenase (Chodat & Bach 1903, in Ber. d. Deut. Chem. Ges. XXXVI. 607): see oxygen and -ase.]
Any enzyme which catalyses the incorporation of molecular oxygen into a substrate; orig. used in the narrowest sense of oxidase.
1903Jrnl. Chem. Soc. LXXXIV. i. 378 Most oxydases contain principles of both types, and it is proposed to retain the term peroxydase for those substances..which are not themselves oxidisers, but impart activity to, and thus destroy, peroxides, whilst the new term, ‘oxygenase’, is proposed for those substances..which are capable of producing hydrogen peroxide, but leave it in an inactive condition. 1920M. W. Onslow in Biochem. Jrnl. XIV. 536 The function of this additional enzyme is to catalyse the oxidation of the catechol substance with the formation of a peroxide... It is proposed to call this second enzyme an oxygenase, a term originally used by Chodat and Bach for the portion of an oxidase which can be replaced by hydrogen peroxide. 1964[see oxidase]. 1971M. F. Mallette et al. Introd. Biochem. viii. 282 Both oxygenases and hydroxylases use O2 to alter substrates... Both classes of enzymes reduce O2 but do it by incorporating oxygen atoms into organic substrates. On the other hand, oxidases reduce O2..and do not incorporate it into organic compounds. |