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单词 pheniprazine
释义 pheniprazine Pharm.|fəˈnɪprəziːn|
[f. phen- + iso- + propyl + hydrazine.]
The compound 1-phenyl-2-hydrazinopropane, C9H14N2, which was formerly used (as the hydrochloride) for the treatment of depression, angina, and hypertension.
1960Jrnl. Amer. Med. Assoc. 2 Apr. 1554/1 Mackinnon and co-workers used pheniprazine to treat a series of 28 patients with the anginal syndrome.1961Lancet 16 Sept. 622/2 It seems probable that pheniprazine was the cause of the jaundice; the total dose was 560 mg. given over sixty days.1971L. E. Hollister in Melmon & Morrelli Clin. Pharmacol. (1972) xi. 459/1 The first hydrazide drug was iproniazid... A later member of the series was pheniprazine (Catron). Both have subsequently been removed from the market because of intolerable toxicity.
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更新时间:2024/12/22 0:41:07