| 释义 |
phenmetrazine Pharm.|fɛnˈmɛtrəziːn|
[f. phenyl + -metr- (f. methyl + hydro-) + azine, constituent parts of the systematic name 2-phenyl-3-methyl-tetrahydro-1,4-oxazine.]
3-Methyl-2-phenylmorpholine, C11H15NO, the hydrochloride of which, a white powder, has been used as an appetite suppressant and is a stimulant of the central nervous system similar to (though weaker than) amphetamine, to which it is chemically related.
1956Amer. Jrnl. Digestive Dis. I. 155 Phenmetrazine has been used clinically in Germany in the management of obesity. 1959Lancet 22 Aug. 152/1 Phenmetrazine (‘Preludin’), a sympathomimetic drug discovered by Thomae and Wick, was first used in 1954 in the treatment of obesity. Since then it has been given in asthma, in parkinsonism, and as a euphoriant. 1962[see herniation]. 1970[see Preludin]. |