释义 |
prednisone Pharm.|ˈprɛdnɪsəʊn| [Prob. f. pregnadiene (f. pregnane + diene) + -isone, after cortisone.] A colourless, crystalline, synthetic steroid, C21H26O5, resembling cortisone but possessing greater glucocorticoid activity, which is used as an anti-inflammatory agent and to depress immune responses, esp. in the treatment of rheumatoid arthritis.
1955Dis. Chest XXVII. 515 Metacortandracin (Metacortin) used in this study and furnished by Schering Corporation, Bloomfield, New Jersey has been re-named Prednisone. 1955[see prednisolone]. 1959S. Duke-Elder Parson's Dis. Eye (ed. 13) xiv. 150 Prednisone and Prednisolone, are often preferable for systemic administration since they are less liable to excite the unfortunate side-effects associated with cortisone. 1965Spectator 1 Jan. 12/3 Prednisone is especially useful for easing the pain of aged arthritics. 1974R. M. Kirk et al. Surgery iv. 58 Generalised disease responds to chemotherapy, usually with a combination of vincristine, mustine, procarbazine and prednisone in pulsed doses. |