| 释义 |
atebrin|ˈætɪbrɪn|
Also (chiefly U.S.) atabrine. (Both are proprietary terms.)
[ad. -ate1 1 c + brine.]
A synthetic antimalarial drug, quinacrine dihydrochloride; also called mepacrine.
The word is recorded from 1913 but was not applied to the anti-malarial drug discovered by the German chemists H. Mauss and F. Mietzsch in 1930 (when it was known by the laboratory name of ‘Erion’) until 1932. See 1933 Klinische Wochenschrift 19 Aug., 1276–8.
[1913Trade Marks Jrnl. 12 Mar. 390 Atebrin. Chemical Substances Prepared for Use in Medicine and Pharmacy..The Bayer Comp., Limited, Manchester.] 1932Lancet 16 Apr. 826/1 Atebrin, originally called erion, has been produced recently by the makers of plasmoquine. 1933Discovery Apr. 118/1 Atebrin, made by the chemists Mietzsch and Mauss..in some experiments..has been more successful than quinine in curing and preventing relapses [of malaria]. 1935F. Stark Let. 17 Mar. in Coast of Incense (1953) i. 91 Decided it must be malaria—took masses of atebrin. 1945Times 1 Sept. 4/3 The sick had few medical supplies and no quinine or atebrin. 1948Chem. Abstr. 1937–46 Index 4073/1 Atabrine. 1957New Yorker 29 June 75/1 The only malaria suppressive available for the Buna campaign was quinine; even atabrine, itself now an outmoded weapon against the disease, was not on hand. 1961J. Heller Catch-22 (1962) xxxviii. 391 I'm sorry about making such a fuss about those Atabrine tablets on the way over. If you want to catch malaria, I guess it's your business, isn't it? |