| 释义 |
Scatchard Biochem.|ˈskætʃɑːd|
[The name of George Scatchard (1892–1973), U.S. physical chemist, who published a form of such analysis in 1949 (Ann. N.Y. Acad. Sci. LI. 660–72).]
Scatchard plot, a graph of the concentration of a solute absorbed by a protein, membrane, cell, or the like against its concentration in the surrounding medium; Scatchard analysis, the use of such graphs to deduce the number and nature of the binding sites on the protein, etc.
1958Edsall & Wyman Biophys. Chem. I. xi. 617 (heading) The Scatchard plot of v /(A) against v . 1970Arch. Biochem. & Biophysics CXLI. 623/2 (caption) Scatchard plot for binding of cytochrome c to normal rat liver mitochondria. 1975Nature 13 Nov. 154/2 (caption) Scatchard plot of insulin-membrane interaction in two representative preparations from 10 control..and 10 diabetic..animals. Ibid. 27 Nov. 339/2 Scatchard analysis of the binding data revealed a class of receptors for 5-α-dihydro⁓testosterone of uniform affinity. 1978Ibid. 12 Oct. 553/2 (caption) Scatchard analysis of interaction between diazepane and ‘endogenous inhibitor’ of Na+-independent 3H-GABA binding. |