| 释义 |
schizonticide Pharm.|skaɪ-, skɪˈzɒntɪsaɪd|
Also schizonto-.
[f. prec. + -icide, as in parricide, tyrannicide, etc., or + -o + -cide.]
A substance that kills schizonts.
1943Jrnl. Infectious Dis. LXXIII. 11/2 In textbooks..quinine and atabrine are considered to be ‘schizonticides’, whereas plasmochin is called a ‘gametocide’. 1944W. N. Bispham Malaria x. 133 Quinine is not as satisfactory as atabrine as a schizonticide in the treatment of P[lasmodium] falciparum. 1963E. Pampana Textbk. Malaria Eradication viii. 211 Drugs that act on the asexual forms, as schizontocides. 1970W. Peters Chemotherapy & Drug Resistance in Malaria v. 139 The main outcome of this investigation was to pinpoint mepacrine as a safe and potent schizontocide, superior to quinine against all human malaria species. 1977Martindale's Extra Pharmacopoeia (ed. 27) 343/2 The 8-aminoquinolines..have a marked effect on gametocytes..but are not effective blood schizonticides.
Hence schizontiˈcidal, -oˈcidal adjs.
1963P. F. Russell et al. Pract. Malariol. (ed. 2) xix. 503 Recent trials with relatively non-toxic schizonticidal drugs..have had some more promising results. 1963Terminol. Malaria (World Health Organization) iv. 66 Schizontocides or blood schizontocides (‘schizontocidal drugs’..) act on asexual erythrocytic stages of the parasite. 1979Amer. Jrnl. Trop. Med. & Hygiene XXVIII. 937/1 By the early 1970's over 200,000 compounds had been screened for blood schizonticidal activity. |