| 释义 |
cephalothin, n. Pharm.|ˈsɛfələʊθɪn|
[Blend of cephalosporin and thio-.]
An antibiotic, C16H16N2O6S2 , derived from cephalosporin, given (usu. by injection as the sodium salt) in the treatment of some bacterial infections.
1962Jrnl. Amer. Chem. Soc. LXXXIV. 3402/1 The sodium salt of 7-(thiophene-2-acetamido)-cephalosporanic acid, which has been given the generic name cephalothin, has received extensive clinical evaluation as a broad spectrum antibiotic. 1976Lancet 13 Nov. 1040/2 She was febrile (39°C) and complained of locked jaw; she was given cephalothin (12 g/day) and gentamicin (120 mg/day). 1981Sci. Amer. June 72/2 The first two semisynthetic cephalosporins, cephalothin from Lilly and cephaloridine from the Glaxo laboratories in Britain, were also active against the penicillin-resistant staphylococcus. 1987Oxf. Textbk. Med. (ed. 2) II. xviii. 111/2 Cephalothin causes acute renal failure only occasionally, and this is less clearly dose related. |