† ˈsplenetize,v.Obs.—1 [f. splenet-ic a. + -ize.] trans. To render splenetic or ill-humoured. 1700S. Parker Philos.Ess. 39 These violent and frequent Alterations in the Weather serve for a perpetual Monitor by discomposing their Constitutions,..and splenetizing the poor Gentlemen all-over.