They may require additional interventions, to manage the greater neurological impairment and also the greater secondary complications.

It has been reported to induce reversible neurological impairment in multiple sclerosis patients, which led to the halt of an ongoing clinical trial.

The symptoms of postperfusion syndrome were initially felt to be permanent, but were shown to be transient with no permanent neurological impairment.

Chronic excess alcohol intake, or alcohol dependence, can lead to a wide range of neuropsychiatric or neurological impairment, cardiovascular disease, liver disease, and malignant neoplasms.

Neurological impairment may be mild, with reduced muscle tone and coordination, or so severe that the person can not stand or walk.