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单词 albright
释义

Albrightn.

Brit. /ˈɔːlbrʌɪt/, /ˈɒlbrʌɪt/, U.S. /ˈɔlbraɪt/, /ˈɑlbraɪt/
Origin: From a proper name. Etymon: proper name Albright.
Etymology: < the name of Fuller Albright (1900–69), U.S. endocrinologist. In sense 2a after French dystrophie d'Albright (P. Seringe and S. Tomkiewicz 1957, in Ann. de Pédiatrie 33 1099/1).Albright described his cases of McCune-Albright syndrome in 1937 ( New Eng. Jrnl. Med. 29 Apr. 727), and those of pseudohypoparathyroidism and pseudopseudohypoparathyroidism in 1942 ( Endocrinology 30 922) and 1952 ( Trans. Assoc. Amer. Physicians 65 337), respectively.
Medicine.
1. Albright's syndrome n. (also Albright syndrome) = McCune–Albright syndrome n.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > other bone disorders
osteocachexy1857
osteitis deformans1877
Paget's disease1889
megalacria1891
osteochondritis dissecans1895
osteogenesis imperfecta1899
von Recklinghausen's disease1910
Albright's syndrome1940
fibrogenesis imperfecta ossium1952
pycnodysostosis1963
McCune–Albright syndrome1966
1940 Q. Cumulative Index Medicus 26 974/2 Osteitis..fibrosa, case with precocious puberty and cutaneous pigmentation (Albright syndrome).
1965 R. H. Durham Encycl. Med. Syndromes 19 Differential diagnosis should exclude hyperparathyroidism..,for in Albright's syndrome considerable portions of the skeleton are unaffected.
2002 Daily Record (Nexis) 19 Aug. 8 Paul has another unusual condition called Albright's Syndrome, which affects the growth of his bones.
2.
a. Albright's dystrophy n. now rare Albright's hereditary osteodystrophy, esp. in the form of pseudopseudohypoparathyroidism.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disordered secretion > [noun] > hormonal disorders
hyperthyroidism1900
hypothyroidism1905
hyperpituitarism1909
hypopituitarism1909
hypoparathyroidism1910
thyrotoxicosis1911
hyperparathyroidism1917
hypogonadism1918
Cushing's disease1934
Cushing's syndrome1934
panhypopituitarism1941
pseudohypoparathyroidism1942
Sheehan's syndrome1950
Stein–Leventhal syndrome1950
pseudopseudohypoparathyroidism1952
aldosteronism1954
hyperaldosteronism1955
Albright's dystrophy1957
Albright's hereditary osteodystrophy1962
1957 Current List Med. Lit. 32 313/2 Albright's dystrophy: pseudo-pseudo-hypoparathyroidism of other authors.
1974 tr. A. Labhart Clin. Endocrinol. 900/2 This term [sc. pseudopseudohypoparathyroidism] is questionable, and attempts have been made to replace it by other terms (dysplasia with calcification of soft tissues, Albright's dystrophy, brachymetacarpal dwarfism).
b. Albright's hereditary osteodystrophy n. (also Albright hereditary osteodystrophy) a familial type of pseudohypoparathyroidism characterized by resistance to parathyroid hormone and by physical abnormalities including short stature, round face, short metacarpal and metatarsal bones, and the presence of subcutaneous ectopic calcifications; (also) pseudopseudohypoparathyroidism.This type of pseudohypoparathyroidism results from mutations in a gene coding for a guanine nucleotide binding protein; pseudopseudohypoparathyroidism is now thought to be an incomplete form of the same disorder in persons inheriting the abnormal gene from the father rather than the mother (as a result of genomic imprinting).
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disordered secretion > [noun] > hormonal disorders
hyperthyroidism1900
hypothyroidism1905
hyperpituitarism1909
hypopituitarism1909
hypoparathyroidism1910
thyrotoxicosis1911
hyperparathyroidism1917
hypogonadism1918
Cushing's disease1934
Cushing's syndrome1934
panhypopituitarism1941
pseudohypoparathyroidism1942
Sheehan's syndrome1950
Stein–Leventhal syndrome1950
pseudopseudohypoparathyroidism1952
aldosteronism1954
hyperaldosteronism1955
Albright's dystrophy1957
Albright's hereditary osteodystrophy1962
1962 Ann. Internal Med. 56 335/1 The ossification or calcification of Albright's hereditary osteodystrophy is subcutaneous.
1986 Clinics Dermatol. 4 4/2 Pseudohypoparathyroidism and pseudopseudohypoparathyroidism are variants of the same abnormality and are jointly referred to as Albright's hereditary osteodystrophy.
2001 New Scientist 13 Jan. 74/1 (advt.) In addition to the investigation of core diseases, the laboratory already has a special interest in Albright's Hereditary Osteodystrophy, Primary Pulmonary Hypertension and deafness.
This entry has been updated (OED Third Edition, September 2012; most recently modified version published online December 2021).
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n.1940
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