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单词 dexamethasone
释义

dexamethasonen.

Brit. /ˌdɛksəˈmɛθəzəʊn/, /ˌdɛksəˈmɛθəsəʊn/, U.S. /ˌdɛksəˈmɛθəˌzoʊn/, /ˌdɛksəˈmɛθəˌsoʊn/
Origin: Formed within English, by compounding. Etymons: English delta-1,9-α fluoro,16-α methyl hydrocortisone, hexadecadrol.
Etymology: < elements of the systematic name delta-1,9-α fluoro,16-α methyl hydrocortisone, and the original generic name hexadecadrol.
Pharmacology.
A synthetic corticosteroid drug used esp. for the treatment of inflammatory, allergic and certain adrenal disorders, and also conditions such as shock and acute cerebral oedema.Dexamethsone is a derivative of hydrocortisone having more powerful pharmacological effects. Chemical name: 1-dehydro-9α-fluoro-16α-methylhydrocortisone; C22H29FO5.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]
epinephrine1899
pituitrin1909
oxytocin1927
Pitocin1929
Pitressin1929
progestin1930
progesterone1935
methyltestosterone1936
pregnenolone1936
hexœstrol1939
stilboestrol1939
hydroxyprogesterone1941
progestogen1941
Premarin1942
hydroxycorticosterone1943
gestagen1948
hydrocortisone1951
cortisol1953
fluorohydrocortisone1954
isophane1954
prednisolone1955
prednisone1955
norethisterone1956
norethynodrel1957
dexamethasone1958
fludrocortisone1958
norethindrone1960
antidiuretic hormone1961
medroxyprogesterone1962
Pergonal1963
mesterolone1965
norgestrel1966
quinestrol1966
pancuronium1967
pentagastrin1967
levonorgestrel1977
1958 Arthritis & Rheumatism Aug. 330 Preliminary results of clinical and laboratory investigations on the effect of dexamethasone in rheumatoid arthritis are encouraging enough to warrant further investigation.
1968 J. H. Burn Lect. Notes Pharmacol. (ed. 9) 95 Dexamethasone is a derivative of hydrocortisone, which is very much more active than hydrocortisone.
1990 Snow Country Mar. 84/2 He conducted his own studies of a prescription drug—dexamethasone—with the potential to relieve the symptoms of acute mountain sickness.
2020 Times 17 June 1/1 Dexamethasone, a decades-old steroid that costs about 50p a day, was found to reduce Covid-19 deaths by up to one third for the sickest patients.
This entry has been updated (OED Third Edition, September 2020; most recently modified version published online March 2022).
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n.1958
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