electroporationn.
/ᵻˌlɛktrəʊpəˈreɪʃn/, /ᵻˌlɛktrəʊpɒˈreɪʃn/, U.S. /əˌlɛktroʊpɔˈreɪʃ(ə)n/, /iˌlɛktroʊpɔˈreɪʃ(ə)n/, /əˌlɛktroʊpəˈreɪʃ(ə)n/, /iˌlɛktroʊpəˈreɪʃ(ə)n/ Biochemistry.
The application of a high-voltage pulse of electricity to cells or protoplasts in order to cause reversible breakdown of the cell membranes, so creating temporary pores through which foreign material may be introduced; the use of this technique as a means of introducing genetic material into cells.
ΚΠ
1982 E. Neumann et al. in EMBO Jrnl. 1 843/1 To a first approximation we may use a two-state model for the ‘electroporation’ process.
1992 Economist 21 Nov. 151/2 He hopes to use the new camera to sort out the optimal conditions for electroporation of different types of cell, and so improve the success rate for introducing foreign substances into the cells.
2004 J. C. Avise Hope, Hype & Reality of Genetic Engin. vii. 155 To improve the cellular entry of naked nuclear DNA, electroporation sometimes is used.
This is a new entry (OED Third Edition, June 2008; most recently modified version published online March 2022).
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n.1982