Arthusn.
/ˈɑːθəs/, U.S. /ˈɑrθəs/ Immunology.
attributive, in the genitive, and †with of. Designating a type of hypersensitivity reaction characterized by oedema, haemorrhage, and necrosis (classically seen as an ulcer of the skin), which occurs after the injection of antigen into a previously sensitized animal and is mediated by the formation of immune complexes. Now esp. in Arthus reaction.
ΚΠ
1908 Jrnl. Exper. Med. 10 25 That the ‘Phenomenon of Arthus’ is in its essential features identical with the ‘Theobald Smith Phenomenon’ is the recently expressed opinion of Otto also.
1921 Lancet 28 May 1138/2 This fundamental discovery, known since as Arthus's phenomenon, is one of the stones on which the immense superstructure of anaphylaxis has since been reared.
1955 Amer. Jrnl. Med. 19 830/2 Obstruction of the smaller branches of the bronchial tree due to a hypersensitivity reaction of the Arthus type.
1967 Canad. Med. Assoc. Jrnl. 30 Sept. 853/1 Animals depleted of polymorphonuclear leukocytes are, to a great degree, protected from..the development of Arthus' reactions.
1977 I. M. Roitt Essent. Immunol. (ed. 3) vi. 167 The Arthus reaction can. be blocked by depletion of complement or of the neutrophil polymorphs.
2002 Science 15 Nov. 1319/3 The team has linked this activity to an inflammatory response called the Arthus reaction in living rats.
Compounds
Arthus-type adj. (attributive) of the nature of or resembling an Arthus reaction.
ΚΠ
1959 Jrnl. Hygiene 57 220 Clearly the major part..of this predominantly early (Arthus-type) reaction was passively transferred with serum.
1977 I. M. Roitt Essent. Immunol. (ed. 3) vi. 167 Intrapulmonary Arthus-type reactions to inhaled antigen appear to be responsible for a number of hypersensitivity disorders.
2000 Vet. Parasitol. 91 288 Chronic cases [of Otodectes mites] in cats may result in Arthus-type hypersensitivity.
This is a new entry (OED Third Edition, December 2008; most recently modified version published online December 2021).
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n.1908