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单词 kynurenic
释义

kynurenicadj.

/kɪnjʊˈrɛnɪk//kʌɪnjʊˈrɛnɪk/
Forms: Also † cyn-.
Etymology: translating German kynuren-säure kynurenic acid (J. Liebig 1853, in Ann. d. Chem. LXXXVI. 125), < Greek κυν- , κύων dog + -uren- , irregularly < οὖρον urine n.1: see -ic suffix 1.
Biochemistry.
kynurenic acid n. a crystalline carboxylic acid, C10H7NO3, that results from the metabolism of tryptophan and is excreted in the urine of man and various animals; 4-hydroxyquinoline-2-carboxylic acid.
ΘΚΠ
the world > matter > chemistry > organic chemistry > acids obtained from animals > [noun] > in urine > miscellaneous others
hippuric acid1831
alkapton1860
hydurilic acid1865
toluric acid1868
kynurenic acid1872
mercapturic acid1879
phenylpyruvic acid1887
EDTA1950
1872 Jrnl. Chem. Soc. 25 1028 When heated by 265° kynurenic acid evolves pure carbon dioxide and melts to a brown liquid.
1889 H. E. Roscoe & C. Schorlemmer Treat. Chem. III. v. 226 When..cynurenic acid is heated with zinc dust in a current of hydrogen, it is reduced to quinoline.
1946 W. R. Fearon Introd. Biochem. (ed. 3) xvii. 351 Surplus dietary tryptophane is excreted in the urine as kynurenine (in rabbits), and as kynurenic acid (in dogs, rats, foxes and wolves).
1971 Pediatrics XLVII. 47/1 This study measured urinary excretion of kynurenic acid..and xanthurenic acid.., two tryptophan metabolites via the kynurenine pathway, in 26 hospitalized children.
This entry has not yet been fully updated (first published 1976; most recently modified version published online December 2020).
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adj.1872
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