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1869 W. Jenner in Brit. Med. Jrnl. 2 Jan. 3/2 Large-lunged emphysema is a very common cause of a moderate degree of displacement.

1907 W. Osler & T. McCrae Mod. Med. III. xix. 757 From the very nature of this process it does not appear that it can be held accountable for the production of the great majority of the cases of large-lunged emphysema.

1958 Amer. Jrnl. Med. 25 14/1 Jenner did point out that small lunged emphysema was less devastating to the patient than its large lunged counterpart.