单词 | melanosis coli |
释义 | > as lemmasmelanosis coli 3. Brown or black discoloration of the mucous membrane of a part of the intestinal tract, esp. the colon, often associated with excessive consumption of anthraquinone laxatives. Chiefly in melanosis coli. ΚΠ 1931 Jrnl. Pathol. & Bacteriol. 34 61 At that time [sc. 1847] Virchow did not coin a special name for the condition but in 1858 he provided a specimen, now in the museum of the Pathological Institute at Berlin, labelled in his own hand-writing ‘melanosis coli’. 1931 Jrnl. Pathol. & Bacteriol. 34 62 The first detailed account of the morbid anatomy of melanosis coli was given by Pick in 1911... Pick adopted the term melanosis coli without being aware of its previous use by Virchow. 1982 Jrnl. Submicrosc. Cytol. 14 389 The pigment in melanosis duodeni resides in the lysosomes of macrophages in the lamina propria. 1992 Carcinogenesis 13 2217 Morphological observation of the intestines also revealed melanosis, crypt abscesses and erosion, becoming more pronounced with length of exposure to the anthraquinone. < as lemmas |
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