methanthelinen.

Brit.

/mᵻˈθanθəliːn/, U.S.

/məˈθænθəˌlin/,

/məˈθænθəl(ə)n/

Origin: Apparently formed within English, by derivation. Etymons: methyl n., xanthene n., English -l-, -ine.

Etymology: Apparently < meth- (in methyl n.: see note s.v. meth- comb. form) + -anthe- (in xanthene n.) + -l- (in systematic name of compound, or perhaps simply epenthetic) + -ine (compare -ine suffix⁵). Compare propantheline n.

Pharmacology.

More fully methantheline bromide. An anticholinergic drug used to treat peptic ulcer, hyperhidrosis, and bladder spasm; N,N- diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]ethanaminium bromide, C₂₁H₂₆BrNO₃.International Nonproprietary Name (1996) and British Approved Name (1997): methanthelinium bromide.

ΚΠ

1951 A. Grollman Pharmacol. & Therapeutics xv. 298 Methantheline..is used in the treatment of duodenal ulcer. It reduces the peristaltic movements of the stomach and inhibits gastric secretion of hydrochloric acid.

1958 J. H. Burn Lect. Notes Pharmacol. (ed. 5) 28 Methantheline (Banthine) and propantheline (Probanthine) are used to relieve the pain of gastric and duodenal ulcers.

1975 Investigative Urol. 12 317 Oxybutynin possesses a notable antispasmodic activity distinct from its anticholinergic activity and stronger than that of atropine, propantheline, or methantheline.

1995 Ann. Pharmacotherapy 29 489 The earliest case reports of systemic therapy for hyperhidrosis described the use of the anticholinergic methantheline bromide.

This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	methantheline
释义	methanthelinen. Brit. /mᵻˈθanθəliːn/, U.S. /məˈθænθəˌlin/, /məˈθænθəl(ə)n/ Origin: Apparently formed within English, by derivation. Etymons: methyl n., xanthene n., English -l-, -ine. Etymology: Apparently < meth- (in methyl n.: see note s.v. meth- comb. form) + -anthe- (in xanthene n.) + -l- (in systematic name of compound, or perhaps simply epenthetic) + -ine (compare -ine suffix⁵). Compare propantheline n. Pharmacology. More fully methantheline bromide. An anticholinergic drug used to treat peptic ulcer, hyperhidrosis, and bladder spasm; N,N- diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]ethanaminium bromide, C₂₁H₂₆BrNO₃.International Nonproprietary Name (1996) and British Approved Name (1997): methanthelinium bromide. ΚΠ 1951 A. Grollman Pharmacol. & Therapeutics xv. 298 Methantheline..is used in the treatment of duodenal ulcer. It reduces the peristaltic movements of the stomach and inhibits gastric secretion of hydrochloric acid. 1958 J. H. Burn Lect. Notes Pharmacol. (ed. 5) 28 Methantheline (Banthine) and propantheline (Probanthine) are used to relieve the pain of gastric and duodenal ulcers. 1975 Investigative Urol. 12 317 Oxybutynin possesses a notable antispasmodic activity distinct from its anticholinergic activity and stronger than that of atropine, propantheline, or methantheline. 1995 Ann. Pharmacotherapy 29 489 The earliest case reports of systemic therapy for hyperhidrosis described the use of the anticholinergic methantheline bromide. This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1951
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