methotrimeprazinen.
/ˌmɛθəʊtrʌɪˈmɛprəziːn/, /ˌmiːθəʊtrʌɪˈmɛprəziːn/, U.S. /ˌmɛθoʊˌtraɪˈmɛprəˌzin/ Pharmacology.
A phenothiazine derivative used as a sedative and analgesic, administered orally (as the maleate) or by injection (as the hydrochloride); 10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine, C19H24N2OS.International Nonproprietary Name (1996): levomepromazine.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > anti-psychotic tranquillizers
tranquillizer1800
thioxanthene1911
phenothiazine1940
piperoxan1950
fluphenazine1959
Melleril1959
thioridazine1959
methotrimeprazine1960
thiothixene1965
molindone1967
pimozide1968
risperidone1988
1960 Brit. Med. Jrnl. 13 Aug. 524/2 Methotrimeprazine, this drug, also called levopromazine, has similar clinical effects and pharmacological actions as chlorpromazine but is nearly twice as potent.
1971 New Scientist 23 Sept. 664/2 Etorphine is combined with the tranquilliser..methotrimeprazine for use on small animals.
1987 Brit. Med. Jrnl. 28 Feb. 554/2 Methotrimeprazine (25–150 mg/24 h) and hyoscine are also effective but cause more sedation.
1999 Hosp. Med. 60 564 Levomepromazine (previously known as methotrimeprazine) has a broad range of beneficial effects in the terminal phase of many illnesses, resulting from its combined antipsychotic, anxiolytic and sedative actions.
This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).
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n.1960