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单词 mischarging
释义

mischargingn.1

Origin: Formed within English, by derivation. Etymons: mis- prefix1, charge v., -ing suffix1.
Etymology: < mis- prefix1 + charge v. + -ing suffix1. Compare charging n.
Obsolete. rare.
The misaiming of a weapon. Cf. charge v. 21a.
ΘΚΠ
the world > space > direction > [noun] > giving direction towards a mark > aim or aiming > aiming amiss
mischarging1548
aiming1912
society > armed hostility > military equipment > operation and use of weapons > action of propelling missile > [noun] > aim or aiming > misaiming
mischarging1548
1548 Hall's Vnion: Edward IV f. ccxlvijv He was with mischarging of a speare..pytyfullye slayne.
This entry has been updated (OED Third Edition, June 2002; most recently modified version published online June 2018).

mischargingn.2

Brit. /ˌmɪsˈtʃɑːdʒɪŋ/, U.S. /ˌmɪsˈtʃɑrdʒɪŋ/
Origin: Formed within English, by derivation. Etymons: mischarge v., -ing suffix1.
Etymology: < mischarge v. + -ing suffix1.
Molecular Biology.
The linking of a transfer RNA molecule and an amino acid that is not specific to it.
ΚΠ
1971 Arch. Biochem. & Biophysics 142 176 New heterologous mischarging reactions with yeast phenylalanyl transfer RNA synthetase.
1972 Proc. National Acad. Sci. U.S.A. 69 3066/2 We expect that tRNA mutations that produce mischarging will be crucial in establishing these patterns.
1988 Science 16 Dec. 1548/3 The most likely factor to influence the extent of mischarging was the concentration of GlnRS [= glutaminyl-tRNA synthetase] present in the cell.
1998 Proc. National Acad. Sci. U.S.A. 95 12834/1 The functional significance of the tRNA mischarging promoted by AspRS2 [= aspartyl-tRNA synthetase 2].
This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).

mischargingadj.

Brit. /ˌmɪsˈtʃɑːdʒɪŋ/, U.S. /ˌmɪsˈtʃɑrdʒiŋ/
Origin: Formed within English, by derivation. Etymons: mischarge v., -ing suffix2.
Etymology: < mischarge v. + -ing suffix2.
Molecular Biology.
Of transfer RNA: that binds with an amino acid whose codon is not complementary to the transfer RNA anticodon.
ΚΠ
1974 Jrnl. Molecular Biol. 83 (title) 333 Mischarging single and double mutants of Escherichia coli..tyrosine transfer RNA.
1988 Protein Sequences Data Anal. 1 479 The single amino acid change responsible for the mischarging phenotype was identified.
1996 Biochemistry 35 601 Unlike other mischarging mutants of GlnRS that have been characterized, it does not exhibit generally relaxed tRNA specificity in vivo.
This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).
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n.11548n.21971adj.1974
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