multidrugadj.

Brit.

/ˈmʌltɪdrʌɡ/, U.S.

/ˈməltiˌdrəɡ/; see also multi- comb. form.

Origin: Formed within English, by compounding. Etymons: multi- comb. form, drug n.¹

Etymology: < multi- comb. form + drug n.¹ Compare multiple-drug adj. at multiple n. and adj. Compounds 2b, triple-drug therapy n. at triple adj. and adv. Additions.

Medicine.

1. Involving or relating to the use of more than one drug, esp. concurrently.

ΚΠ

1915 Medical Council Oct. 63/2 It will do the multi-drug user a world of good to see how simple, after all, modern medication has become.

1953 Milwaukee (Wisconsin) Jrnl. 14 Feb. (This Week Mag.) 24/1 The secret of fighting resistant houseflies..is to mix your weapons and use multi-drug combinations that can wipe out all enemies in a single blitz attack.

1966 Ann. N.Y. Acad. Sci. 135 823 (title) Multi-drug therapy including ethambutol in retreatment of pulmonary tuberculosis.

1988 Proc. National Acad. Sci. U.S.A. 85 1917 The cost of multidrug therapy to combat emergent drug resistance of Mycobacterium leprae is high.

1998 Guardian 21 Dec. 8/2 The researchers call this expensive kind of multi-drug habit a ‘rock repertoire’.

2. Designating resistance to the action of a number of drugs.

ΚΠ

1967 E. Afr. Med. Jrnl. 44 232 (heading) Multi-drug resistance.

1981 Proc. National Acad. Sci. U.S.A. 78 3654 Correlation of double-minute chromosomes with unstable multidrug cross-resistance in uptake mutants of neuroblastoma cells.

1993 Brit. Jrnl. Surg. 80 124/2 P-Glycoprotein has been implicated as a cause of multidrug resistance in a variety of neoplasms.

Compounds

multidrug-resistant adj. designating bacteria or a disease with resistance to a number of drugs; abbreviated MDR.

ΚΠ

1966 Amer. Jrnl. Trop. Med. & Hygiene 15 823/1 The treatment of the multi-drug-resistant strains of P. falciparum.

1999 New Scientist 28 Aug. 21/3 A new antibiotic called linezolid could be a potent weapon against multidrug resistant bacteria.

This is a new entry (OED Third Edition, March 2003; most recently modified version published online March 2022).

单词	multidrug
释义	multidrugadj. Brit. /ˈmʌltɪdrʌɡ/, U.S. /ˈməltiˌdrəɡ/; see also multi- comb. form. Origin: Formed within English, by compounding. Etymons: multi- comb. form, drug n.¹ Etymology: < multi- comb. form + drug n.¹ Compare multiple-drug adj. at multiple n. and adj. Compounds 2b, triple-drug therapy n. at triple adj. and adv. Additions. Medicine. 1. Involving or relating to the use of more than one drug, esp. concurrently. ΚΠ 1915 Medical Council Oct. 63/2 It will do the multi-drug user a world of good to see how simple, after all, modern medication has become. 1953 Milwaukee (Wisconsin) Jrnl. 14 Feb. (This Week Mag.) 24/1 The secret of fighting resistant houseflies..is to mix your weapons and use multi-drug combinations that can wipe out all enemies in a single blitz attack. 1966 Ann. N.Y. Acad. Sci. 135 823 (title) Multi-drug therapy including ethambutol in retreatment of pulmonary tuberculosis. 1988 Proc. National Acad. Sci. U.S.A. 85 1917 The cost of multidrug therapy to combat emergent drug resistance of Mycobacterium leprae is high. 1998 Guardian 21 Dec. 8/2 The researchers call this expensive kind of multi-drug habit a ‘rock repertoire’. 2. Designating resistance to the action of a number of drugs. ΚΠ 1967 E. Afr. Med. Jrnl. 44 232 (heading) Multi-drug resistance. 1981 Proc. National Acad. Sci. U.S.A. 78 3654 Correlation of double-minute chromosomes with unstable multidrug cross-resistance in uptake mutants of neuroblastoma cells. 1993 Brit. Jrnl. Surg. 80 124/2 P-Glycoprotein has been implicated as a cause of multidrug resistance in a variety of neoplasms. Compounds multidrug-resistant adj. designating bacteria or a disease with resistance to a number of drugs; abbreviated MDR. ΚΠ 1966 Amer. Jrnl. Trop. Med. & Hygiene 15 823/1 The treatment of the multi-drug-resistant strains of P. falciparum. 1999 New Scientist 28 Aug. 21/3 A new antibiotic called linezolid could be a potent weapon against multidrug resistant bacteria. This is a new entry (OED Third Edition, March 2003; most recently modified version published online March 2022). < adj.1915
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