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单词 optochin
释义

optochinn.

Brit. /ˈɒptətʃɪn/, U.S. /ˈɑptəˌtʃɪn/
Forms: 1900s– optochin, 1900s– optochine, 1900s– optoquine (rare).
Origin: A borrowing from German. Etymon: German Optochinum.
Etymology: < German Optochinum (M. Goldschmidt 1913, in Klin. Monatsbl. f. Augenheilkunde 51 ii. 449; now usually Optochin ) < opto- opto- comb. form (from its use in treating eye infections) + Chin- (in Chinin quinine n.) + -um, after Latin nouns in -um.The form optoquine in quot. 1925 shows the influence of quinine n.
Pharmacology.
A bactericidal derivative of quinine now used chiefly as a diagnostic test for Streptococcus pneumoniae; dihydrocupreine ethyl ether, C21H28O2N2.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bactericide > specific
alexin1891
typholysin1902
optochin1914
marfanil1942
1914 Chem. Abstr. 8 3692 (heading) Chemotherapy of the pneumococci infections of the eye, particularly of the ulcus serpens by means of optochin ointment (ethylhydrocuprein).
1925 C. H. Browning Bacteriol. xi. 252 The only success obtained in generalised infections due to the ordinary bacteria is the cure of pneumococcal infection in mice by means of Morgenroth's ‘optoquine’.
1953 I. Heilbron & H. M. Bunbury Dict. Org. Compounds (rev. ed.) IV. 23/2 Optochine (dihydrocupreine ethyl ether).
1970 Jrnl. Gen. Microbiol. 61 138 Assays were made..for the single transformant, to erythromycin, streptomycin, and optochin resistances.
2002 Diagnostic Microbiol. & Infectious Dis. 42 263 Standard identification of Streptococcus pneumoniae by optochin and bile solubility testing can lead to ambiguous results.
This entry has been updated (OED Third Edition, June 2004; most recently modified version published online March 2022).
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n.1914
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