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单词 osteodystrophy
释义

osteodystrophyn.

Brit. /ˌɒstɪəʊˈdɪstrəfi/, U.S. /ˈˌɑstioʊˈdɪstrəfi/
Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: osteo- comb. form, dystrophy n. at dys- prefix .
Etymology: < osteo- comb. form + dystrophy n. at dys- prefix , after German Osteodystrophia (J. von Mikulicz 1905, in Verhandl. der Ges. Deutsch. Naturforscher u. Ärzte 76 ii. Med. Abt. 108). Compare earlier chondrodystrophy n., muscular dystrophy n.
Medicine and Veterinary Medicine.
Any of a diverse group of disorders characterized by generalized or localized abnormality in the structure of bone; esp. that caused by hyperparathyroidism (also called osteitis fibrosa, osteitis fibrosa cystica).renal osteodystrophy: osteodystrophy resulting from secondary hyperparathyroidism and abnormal vitamin D metabolism in chronic renal failure.
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the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > decay or erosion
caries1634
cariosity1638
spina ventosa1684
cariousness1818
osteoporosis1841
rarefaction1850
osteolysis1875
osteitis fibrosa1910
porosis1926
osteodystrophia fibrosa1928
osteodystrophy1930
1930 Jrnl. Exper. Med. 52 669 (title) Experimental fibrous osteodystrophy (ostitis fibrosa) in hyperparathyroid dogs.
1932 W. Boyd Text-bk. Pathol. xxxi. 883 Among these..osteitis fibrosa, osteitis deformans, osteomalacia, rickets,..hereditary chondrodysplasia, and marble bones may be mentioned. As they are disorders of the growth of bone they may be considered together under the heading of the osteodystrophies.
1953 Jrnl. Pathol. & Bacteriol. 65 302 In severe renal osteodystrophy the local upheaval in bone formation may result in the development of lesions resembling either osteopetrosis or Paget's disease.
1963 K. V. F. Jubb & P. C. Kennedy Pathol. Domest. Animals I. i. 8/1 The classical osteodystrophies are rickets, osteomalacia, and osteodystrophia fibrosa.
1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. i. xxii. 10/2 The clinical features of renal osteodystrophy are most marked in children, in whom there is growth retardation.
1983 D. J. Weatherall et al. Oxf. Textbk. Med. I. xii. 28/2 Lesions found in the jaws...(e) osteodystrophies: giant-cell reparative granuloma, brown tumour of hyperparathyroidism, fibrous dysplasia, and Paget's disease.
2003 Jrnl. Clin. Investig. 112 1255 Patients with pseudohypoparathyroidism type Ib have hypocalcemia and hyperphosphatemia due to renal parathyroid hormone resistance, but lack physical features of Albright hereditary osteodystrophy.
This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).
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n.1930
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