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单词 phenacaine
释义

phenacainen.

Brit. /ˈfiːnəkeɪn/, /ˈfɛnəkeɪn/, U.S. /ˈfinəˌkeɪn/, /ˈfɛnəˌkeɪn/
Forms: 1900s– phenacaine, 1900s– phenocain, 1900s– phenocaine.
Origin: Formed within English, by compounding. Etymons: pheno- comb. form, English -a- , -caine comb. form.
Etymology: < pheno- comb. form + -a-, connective element + -caine comb. form.
Pharmacology. Now rare.
A local anaesthetic, used esp. for the eye. Also called holocaine.Chemical name: N,N′-bis-(p-ethoxyphenyl)acetamidine, C18H22N2O2.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > anaesthetic > [noun] > local > for the eye
holocaine1897
phenacaine1907
amethocaine1941
1907 Brit. Pharmaceut. Codex 260 Many synthetic substitutes for cocaine have been suggested for use as local anæsthetics, including..phenacaine (Holocaine).
1911 Brit. Pharmaceut. Codex 312 Phenocaine.
1920 W. Martindale & W. W. Westcott Extra Pharmacopœia (ed. 17) I. 331 Holocain Hydrochloride... Syn. Phenocain.
1968 J. H. Burn Lect. Notes Pharmacol. (ed. 9) 62 Phenacaine (holocaine) is prompt in action and is used especially for the eye.
1981 Proc. National Acad. Sci. U.S.A. 78 795/1 Local anesthetics such as dibucaine, QX572, tetracaine, and phenacaine..inhibit the specific calmodulin-dependent stimulation of erythrocyte Ca3+-ATPase..from brain and heart.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1907
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