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单词 phagolysosome
释义

phagolysosomen.

Brit. /faɡə(ʊ)ˈlʌɪsə(ʊ)səʊm/, U.S. /ˌfæɡoʊˈlaɪsəˌsoʊm/
Origin: Formed within English, by compounding. Etymons: phagocyte n., lysosome n.
Etymology: < phago- (in phagocyte n.) + lysosome n. Compare earlier phagosome n.With phagolysosomal adj. at Derivatives compare phagosomal adj. at phagosome n. Derivatives and earlier lysosomal adj. at lysosome n. Derivatives.
Biology and Medicine.
A structure formed in the cytoplasm of a cell by the fusion of a phagosome and a lysosome.
ΘΚΠ
the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents
raphide1831
body1839
raphid1863
mucigen1874
cell sap1875
globoid1875
raphis1879
pyrenoid1883
mucinogen1884
plastid1885
molluscum corpuscle1886
hyalosome1889
molluscum body1892
statolith1892
dictyosome1893
centrosome1895
Nissl body1898
Nissl granule1898
Nissl substance1899
archespore1901
blepharoplast1907
liposome1910
statocone1910
kinetosome1912
Golgi body1916
kinetoplast1925
lipochondrion1936
microsome1943
kappa1945
Pappenheimer body1947
microbody1954
lysosome1955
siderosome1957
ribosome1958
melanosome1961
cisterna1962
microtubule1962
plasmalemmasome1962
phagolysosome1963
informosome1964
monosome1964
mucocyst1965
peroxisome1965
rhoptry1967
spectrin1968
virosome1970
1963 W. Straus in A. V. S. de Reuck & M. P. Cameron Lysosomes 166 The term ‘phagosomes’ was used to characterize the segregating ability of granules; the term ‘lysosomes’ was used to indicate the contents of hydrolytic enzymes in the granules.., and the terms ‘lyso-phagosomes’ or ‘phago-lysosomes’ were used when both these properties were described for the same granules.
1973 R. G. Krueger et al. Introd. Microbiol. xxiii. 584/1 The phagolysosome, containing the remains of the foreign object is then either eliminated from the cell or is left in the cytoplasm.
1994 Science 29 July 613/1 Shigella flexneri undergoes a different interaction with its host to cause dysentery; these bacteria are taken up in phagolysosomes and must exit from this vacuole into the cytoplasm to cause disease.
2002 Nature 24 Jan. 373/1 When B. anthracis spores are inhaled they lodge in the lungs, where they are ingested by macrophages... The spores are not destroyed but germinate and multiply within membranous compartments called phagolysosomes in macrophages.

Derivatives

ˌphagolysoˈsomal adj.
ΘΚΠ
the world > life > biology > substance > cell > cell organelle or contents > [adjective] > other organelles or contents
mucigenous1886
centrosomic1895
chromosomal1895
microsomal1897
lipochondrial1946
kinetosomal1949
microsomal1951
lysosomal1957
ribosomal1959
microtubular1963
peroxisomal1967
phagolysosomal1975
phagosomal1975
1973 Investigative Ophthalmol. 12 635 (title) The phagolysomal [sic] system of the pigment epithelium.]
1975 Nature 3 July 48/2 The phagolysosomal membrane was invariably applied closely to the surface of the enclosed yeast cell.
1985 Science 13 Sept. 1101/1 The data presented here demonstrate a potentially critical adaptation of L. donovani amastigotes, permitting growth in the phagolysosomal compartment of infected macrophages.
2004 Infection & Immunity 76 3524 Fc-dependent antibodies protected against R[ickettsia] conorii infection of endothelium and macrophages by opsonization that inhibited phagosomal escape and resulted in phagolysosomal killing.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1963
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