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单词 pizotifen
释义

pizotifenn.

Brit. /pᵻˈzəʊtᵻfɛn/, U.S. /pəˈzoʊdəˌfɛn/
Origin: Formed within English, by compounding. Etymons: piperidine n., benzo- comb. form, thiophene n. at thio- comb. form 1.
Etymology: < pi- (in piperidine n.) + -zo- (in benzo- comb. form) + -tifen, representing thiophene n. at thio- comb. form 1, elements of the systematic name.
Pharmacology.
A tricyclic drug with blocking properties at histamine and serotonin receptors, given orally in tablet form as a prophylactic in some cases of recurrent migraine; C19H21NS.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > prophylactic medicine > [noun] > specific
amantadine1964
pizotifen1969
1969 WHO Chron. 23 439 Pizotifen.
1977 Lancet 11 June 1259/2 We have done a small pilot trial of pizotifen combined with maprotiline (‘Ludiomil’) in patients with depression.
1988 Pharmacology 37 252/1 In our studies, the 5-HT antagonists cyproheptadine and pizotifen..inhibited the pressor effect of 5-HT and DHE in a noncompetitive manner.
1998 Zest Sept. 54/1 Drugs such as beta blockers (propranolol), tricyclic antidepressants, calcium channel blockers and pizotifen can be used to help prevent migraines in people who suffer more than four attacks a month.
This entry has been updated (OED Third Edition, June 2006; most recently modified version published online March 2022).
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n.1969
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更新时间:2025/1/30 13:34:27