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单词 plasmalogen
释义

plasmalogenn.

Brit. /plazˈmalədʒ(ə)n/, U.S. /plæzˈmælədʒ(ə)n/
Origin: A borrowing from German. Etymon: German Plasmalogen.
Etymology: < German Plasmalogen (R. Feulgen & K. Voit 1924, in Pflügers Arch. f. ges. Physiol. 206 399) < Plasmal plasmal n. + -ogen -ogen comb. form.
Biochemistry.
Any of a class of phospholipids that yield an aldehyde on mild hydrolysis, having an unsaturated ether linkage in place of one of the fatty acid ester linkages. Cf. plasmal n.
ΚΠ
1925 Chem. Abstr. 19 1155 Throughout the protoplasm of animal tissues there is to be found, very widely disseminated, a substance of lipoid character, insol[uble] in water but sol[uble] in org[anic] solvents and extractable by alc[ohol], termed plasmalogen. When subjected to acids..this substance is split into undetd. components termed plasmal.
1953 A. G. E. Pearse Histochem. ix. 211 Exposure of tissues to formalin for more than 6 hours would hydrolyse plasmalogen to plasmal, but that further exposure would destroy all the liberated plasmal.
1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. x. 5/1 The plasmalogens have an unsaturated ether group, rather than an ester group, on the α position [of the glycerol molecule]. Those of ethanolamine and choline form a big proportion of the phospholipids of brain and heart.
1993 Analyt. Biochem. 213 140/2 Plasmalogens..are phospholipids with an alk-1-enyl (vinyl ether) bond in the sn-1 position and comprise a major fraction of the phospholipid constituents of the mammalian sarcolemma.

Derivatives

plasmaloˈgenic adj.
ΚΠ
1939 Chem. Abstr. 33 8635 This fraction contg. plasmalogenic acid (I) increases with the time of alk[aline] hydrolysis.
1991 Arch. Biochem. & Biophysics 286 346/2 Specific protein—lipid interactions exist, favoring the association of plasmalogenic aminophospholipids with the calcium pump protein.
This entry has been updated (OED Third Edition, June 2006; most recently modified version published online March 2022).
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