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单词 prednisone
释义

prednisonen.

Brit. /ˈprɛdnᵻzəʊn/, U.S. /ˈprɛdnəˌzoʊn/, /ˈprɛdnəˌsoʊn/
Origin: Probably formed within English, by compounding. Etymons: English pregnadiene , cortisone n.
Etymology: Probably < pre- , -d- , and -n- (in pregnadiene, element of the molecular structure: see note at sense ( < pregna- (in pregnane n.) + diene n.) + -isone (in cortisone n.).
Pharmacology.
A synthetic corticosteroid with medical uses similar to those of prednisolone.Chemical name: 1,4-pregnadiene-17α,21-diol-3,11,20-trione;C21H26O5.Prednisone is in itself biologically inactive but is converted to prednisolone in the liver.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]
epinephrine1899
pituitrin1909
oxytocin1927
Pitocin1929
Pitressin1929
progestin1930
progesterone1935
methyltestosterone1936
pregnenolone1936
hexœstrol1939
stilboestrol1939
hydroxyprogesterone1941
progestogen1941
Premarin1942
hydroxycorticosterone1943
gestagen1948
hydrocortisone1951
cortisol1953
fluorohydrocortisone1954
isophane1954
prednisolone1955
prednisone1955
norethisterone1956
norethynodrel1957
dexamethasone1958
fludrocortisone1958
norethindrone1960
antidiuretic hormone1961
medroxyprogesterone1962
Pergonal1963
mesterolone1965
norgestrel1966
quinestrol1966
pancuronium1967
pentagastrin1967
levonorgestrel1977
the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > immuno-suppressant > specific
prednisolone1955
prednisone1955
rapamycin1975
cyclosporin1976
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological
hydroxycorticosterone1943
hydrocortisone1951
cortisol1953
prednisolone1955
prednisone1955
triamcinolone1957
mefenamic acid1962
ibuprofen1967
tetracosactrin1967
1955 Dis. Chest 27 515 Metacortandracin (Metacortin) used in this study and furnished by Schering Corporation, Bloomfield, New Jersey has been re-named Prednisone.
1974 R. M. Kirk et al. Surgery iv. 58 Generalised disease responds to chemotherapy, usually with a combination of vincristine, mustine, procarbazine and prednisone in pulsed doses.
1990 D. Ackerman Nat. Hist. Senses i. 43 She took a risky step and allowed a doctor to give her prednisone, an anti-inflammatory steroid, in an effort to shrink the swelling near olfactory nerves.
2002 Equus Mar. 56/1 The corticosteroid prednisone has been prescribed to horses with heaves with the intention of reducing airway inflammation.
This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022).
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n.1955
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