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单词 pregnane
释义

pregnanen.

Brit. /ˈprɛɡneɪn/, U.S. /ˈprɛɡˌneɪn/
Origin: A borrowing from German. Etymon: German Pregnan.
Etymology: < German Pregnan (A. Butenandt 1930, in Berichte der Deutsch. Chem. Ges. 63 660) < Pregnan- (in Pregnandiol pregnanediol n.), with ending probably reanalysed as -an -ane suffix2.
Chemistry.
A tetracyclic saturated hydrocarbon, C21H36, which has two stereoisomeric forms and whose molecule is the framework of those of a group of steroids, including progesterone and pregnanediol; spec. the 5β-isomer. Also: any substituted compound having this molecular framework.
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the world > matter > chemistry > organic chemistry > hydrocarbons > [noun] > cyclic hydrocarbons > others
heveëne1838
menthene1838
carotene1861
stilbene1868
mesityl1879
naphthene1884
tetramethylene1885
hexamethylene1887
pentamethylene1887
irene1894
pregnane1932
adamantane1933
aldrin1949
sterane1951
norbornane1952
1932 Ann. Rep. Progress Chem. 28 237 On oxidation there was formed the saturated diketone, C21H32O2, pregnandione, and by Clemmensen reduction of the latter A. Butenandt, F. Hildebrandt, and H. Brücher have obtained the corresponding hydrocarbon, C21H36, pregnane.
1959 I. L. Finar Org. Chem. (ed. 2) II. xi. 456 The molecular rotation of any steroid is considered as the sum of the rotation of the fundamental structure (which is the parent hydrocarbon cholestane, androstane, or pregnane) and the rotations contributed by the functional groups.
1960 L. T. Samuels in D. M. Greenberg Metabolic Pathways I. xi. 432 The two 21-carbon compounds are 5α-pregnane (allopregnane)..and 5β-pregnane (pregnane).
1982 J. B. Harborne Introd. Ecol. Biochem. (ed. 2) vii. 197 The water-beetle toxins are pregnane derivatives.
2001 Steroids 66 875 From 40 g of dried feces a total of 33 pregnanes in the C21O2 series..were identified.
This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022).
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n.1932
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