单词 | pyrrolidine |
释义 | pyrrolidinen. Chemistry. A weakly basic, pungent, heterocyclic liquid obtained by catalytic reduction of pyrrole; any substituted derivative of this.The pyrrolidine molecule is a five-membered saturated ring containing one nitrogen atom, (CH2)4NH. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > containing nitrogen > pyrrolidine pyrrolidine1885 1885 Jrnl. Chem. Soc. 48 ii. 1243 Pyrrolidine..C4NH9, is obtained with other products from hydropyrroline in the above reaction; it shows great similarity in properties to piperidine, hence the name given to it. 1926 H. G. Rule tr. J. Schmidt Text-bk. Org. Chem. 532 Certain important degradation products of the coca and atropa alkaloids have been identified as carboxylic acids of pyrrolidine. 1976 A. Streitwieser & C. H. Heathcock Introd. Org. Chem. xxxv. 1065 Pyrrolidine and piperidine are typical secondary amines. 1994 New Scientist 16 Apr. 8/1 The chemical extracted from the seeds and leaves of the leguminous tree Lonchocarpus costaricaenisi is a pyrrolidine alkaloid called DMDP, which has a structure that mimics a sugar. Compounds pyrrolidine nucleus n. = pyrrolidine ring n. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > containing nitrogen > pyrrolidine > pyrrolidine ring pyrrolidine ring1898 pyrrolidine nucleus1913 1913 T. A. Henry Plant Alkaloids 3 Nicotine contains both a pyridine and a pyrrolidine nucleus. 1956 I. L. Finar Org. Chem. II. xiv. 531 The presence of this pyrrolidine nucleus also accounts for the formation of pyrrole when nicotine zincichloride is distilled. 1995 Jrnl. Medicinal Chem. 38 1505 Various groups were appended to the nitrogen of the pyrrolidine nucleus to enable structure-activity relationships to be assessed. pyrrolidine ring n. a saturated ring of four carbon atoms and one nitrogen. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > containing nitrogen > pyrrolidine > pyrrolidine ring pyrrolidine ring1898 pyrrolidine nucleus1913 1898 Lancet 23 July 199/1 That atropine very probably contains a pyrrolidine ring has only recently been shown. 1963 T. Robinson Org. Constit. Higher Plants xii. 256 Leete..using 1, 4-labelled putrescine fed to tobacco found that it was an efficient precursor of the pyrrolidine ring in nicotine. 1992 Jrnl. Molecular Liquids 51 67 A small proportion of the complexes are formed on the nitrogen atom of the pyrrolidine ring. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < |
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