单词 | quinide |
释义 | quiniden. Chemistry. A crystalline lactone derived from quinic acid. Also: any substituted derivative of this compound, examples of which are present in roasted coffee.Quinide is a bicyclic γ-lactone, C7H10O5. ΚΠ 1864 H. Watts tr. L. Gmelin Hand-bk. Chem. XVI. 225 Kinic acid heated 220–225°..loses water and is converted into kinide. 1894 Watts' Dict. Chem. IV. 374 Quinide is acid in reaction, and is reconverted by bases into quinic acid. 1953 I. Heilbron & H. M. Bunbury Dict. Org. Compounds (rev. ed.) IV. 298/1 Quinide (γ-Lactone of quinic acid). 1987 Clin. & Exper. Pharmacol. & Physiol. 14 785 The synthesis and biological testing of each quinide isomer will establish which is responsible for the opiate receptor activity of instant coffee. 2003 Jrnl. Nutrition 133 3529/2 Loss of a water molecule and the formation of an internal ester bond from chlorogenic acids results in nonacidic quinolactones, or quinides. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < n.1864 |
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