1824 Lancet 26 June 404/2 He does not enter into any details on the pharmaceutical preparations, or the chemical properties of Quinine.

1859 G. Wilson & A. Geikie Mem. E. Forbes iv. 127 A few grains of silky white crystals of quinine were found sufficient to dispel the fever.

1887 Athenæum 19 Feb. 260/1 Antifebrin is stated to be more effective than quinine in reducing fever.

1933 Discovery Apr. 118/1 Atebrin, made by the chemists Mietzsch and Mauss..has been more successful than quinine in curing and preventing relapses [of malaria].

1967 Canad. Med. Assoc. Jrnl. 15 July 121/1 Even quite distinctive tastes may be masked by the addition of small amounts of a substance such as quinine, but this must be thoroughly mixed with the other constituents.

2005 Independent 5 Nov. (Mag.) 65/1 Fever-Tree Indian Tonic Water uses natural quinine harvested from a fever-tree plantation in east Africa.

1869 Nature 23 Dec. 212/2 Efforts of the English Government to establish the quinine-producing plants of South America in our Indian possessions have excited very general interest.

1880 C. R. Markham Peruvian Bark 249 The tree has peculiarities not possessed by any other quinine-producing species.

2002 D. Cline & B. Michel Skeeter Beaters iv. 99 Quinine, available in limited quantity because the Japanese had swallowed up most of the quinine producing countries in the Pacific, would be administered only to those most severely disabled by malaria.

1853 J. Pereira et al. Elements Materia Medica (ed. 3) II: Pt. ii. 1621 The inferior, but cheaper, quinine-yielding barks of Carabaya, Bolivia, and New Granada.

1880 C. R. Markham Peruvian Bark 216 The richest of quinine yielding trees.

2005 R. Gupta in V. L. Chopra & K. V. Peter Handbk. Industr. Crops iv. 144 It [sc. Cinchona calisaya Wedd]..was replaced by the more consistent quinine-yielding C[inchona]ledgeriana.

1861 New Amer. Cycl. XIII. 709/1 This species of the tree, which is common in New Granada, is unknown in the region where the true quinine bark is obtained.

1884 F. O. Bower & D. H. Scott tr. H. A. de Bary Compar. Anat. Phanerogams & Ferns 537 Examples are afforded..by the Quinine barks.

1995 Southeast Asian Jrnl. Trop. Med. & Public Health 26 421 The only suspected antiprotozoal drug is an antimalarial—Alsonia scholaris (‘dita’ or Australian quinine bark).

1882 R. Bentley Man. Bot. (ed. 4) ii. iii. 664 Garrya Fremontii, a native of California, is known as the Quinine Bush from its leaves being used in fevers and ague.

1894 G. Boothby On Wallaby 215 The only vegetation being Quinine bushes (a tall slender tree, with a rough dark bark and glossy leaves).

1908 G. B. Sudworth Forest Trees Pacific Slope 416 Quinine bush [sc. Garrya elliptica] gets its name from its bitter bark, leaves, and, especially, fruit.

1986 K. Brennan Wildflowers of Kakadu 46 Common, widespread shrubs are the Quinine Bush Petalostigma quadriloculare, the Turkey Bush [etc.].

1876 Lancet 11 Nov. 705/1 The quinine flower is intensely bitter and yields its principles to water and alcohol.

1931 M. Grieve Mod. Herbal I. 184/2 S[abatia] Elliottii is known as the Quinine Flower, its properties resembling quinine.

1958 M. L. Jacobs & H. M. Burlage Index of Plants N. Carolina 99 Sabatia elliottii..Quinine flower; quinine plant; quinine herb... This herb grows in eastern and central North Carolina. It has been used in medicine.

1877 H. Watts Dict. Chem. (new ed.) V. 23 They [sc. the sulphates of cinchonine and cinchonidine] may be recognised by the following quinine-test of Liebig.

1884 G. M. Sternberg Malaria & Malarial Dis. 253 We..will often be obliged to reserve our diagnosis until by the successful application of the quinine test we are able to demonstrate that the disease is malarial.

1919 L. Rogers Fevers in Tropics (ed. 3) 47 The latter disease can be readily excluded by the quinine test.

1994 Pharmacol. Biochem. & Behavior 47 74/1 Four days after the quinine test, rats received the first of three conditioning/testing TR [= taste reactivity] tests.

1838 Lancet 13 Jan. 550/1 Another great objection to the use of quina, is its production of a remarkable affection of the head; in some cases vertigo, tinnitus aurium, mental delusions, flushed face, bleeding at the nose, and a variety of symptoms which have been recognised by some medical writers under the name of ‘Quininism’.

1865 A. P. Merrill Lect. Fever v. 72 Always taking care to reduce the dose or to prolong the intervals between them, whenever decided quininism is produced.

1936 Trans. Royal Soc. Trop. Med. & Hygiene 30 112 The doses decided upon were those which were regarded as likely to give good results without causing too great a number to drop out on account of quininism.

1890 J. S. Billings National Med. Dict. I. 266/1 Chininometry, quininometry.

1858 Jrnl. Royal Geogr. Soc. 28 219 We..were duly quinined by Mr. Frost, the intelligent medical officer attached to the consulate.

1879 J. M. Keating Hist. Yellow Fever Epidemic 73 A sick person with a moist skin yields readily to the ordinary treatment, and can be purged and quinined to one's heart's content.

1927 Bulletin (Glasgow) 18 Mar. 5/5 The ‘choleric colonel from India’..is apparently more sinned against than sinning. His medical man has ‘quinined’ him.

1863 R. F. Burton Wanderings W. Afr. II. ix. 142 Re-entering the hotel, we refreshed ourselves with brandy-pawnee, the pawnee being Patent Quinined Water, which has a high local reputation.

1951 M. B. Jacobs Chem. & Technol. Food & Food Products (ed. 2) III. 2416 The quinined dessert wines (usually based on red dessert wines).

1977 Evolution 31 216/2 Quinined banana slices were only moderately bitter in our experiment.