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单词 selective serotonin reuptake inhibitor
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selective serotonin reuptake inhibitor
selective serotonin reuptake inhibitor n. Pharmacology any of a class of psychoactive drugs that act by inhibiting the reuptake into presynaptic nerve cells of the neurotransmitter serotonin, and are used chiefly in the treatment of depression and anxiety disorders; abbreviated SSRI.
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1978 Life Sci. 22 1827 The selective serotonin reuptake inhibitor, Org 6582, inhibits heterosexual copulatory behavior in castrated testosterone-treated male rats.
1993 Harper's Mag. May 54 In 1978 Pfizer scientists first synthesized sertraline hydrochloride, a ‘selective serotonin reuptake inhibitor’, which increases activity in brain synapses.
2004 New Statesman 6 Sept. 11/2 The new-generation drugs are selective serotonin reuptake inhibitors or SSRIs. (Serotonin is the brain chemical associated with happiness.)
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