succinylcholinen.
/ˌsʌksɪnʌɪlˈkəʊliːn/ Pharmacology.
The ion [—CH2COO·(CH2)2+N(CH3)3]2 formed by esterification of succinic acid with choline; also, a halogen salt of this, given intravenously as a short-acting muscle relaxant and local anæsthetic; = suxamethonium n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > depressor of muscular action > specific drugs
tubocurarine1898
Anectine1950
succinylcholine1950
suxamethonium1953
the world > health and disease > healing > medicines or physic > medicines for specific purpose > anaesthetic > [noun] > local > specific drugs
cocaine1874
drumine1886
eucaine1896
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alypin1905
novocaine1905
procaine1918
Nupercaine1929
Percaine1930
pantocaine1931
pontocaine1935
tetracaine1943
xylocaine1946
cinchocaine1947
lidocaine1949
Anectine1950
succinylcholine1950
Scoline1952
suxamethonium1953
lignocaine1954
1950 Chem. Abstr. 44 2124 It is shown that succinyl choline produces strong curarizing effects.
1952 Lancet 21 June 1226/2 Succinylcholine chloride (‘Scoline’) was given intravenously.
1965 J. Pollitt Depression & its Treatm. vi. 80 Occasionally recovery from succinyl choline is delayed and artificial respiration required for an extended period.
1974 M. C. Gerald Pharmacol. iii. 52 Alcohol..and the skeletal muscle relaxant succinylcholine are broken down by the enzymes alcohol dehydrogenase and pseudocholinesterase, respectively.
This entry has not yet been fully updated (first published 1986; most recently modified version published online December 2020).
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n.1950