thiaziden.

Brit.

/ˈθʌɪəzʌɪd/, U.S.

/ˈθaɪəˌzaɪd/

Etymology: < thi- (in thio- comb. form) + az- (in azine n.) + -ide (in oxide n.), elements in the systematic name of the parent compound.

Pharmacology.

Any of a class of drugs derived from 1,2,4-benzothiadiazine-1,1-dioxide that increase the excretion of sodium and chloride and are used as diuretics and as auxiliary hypotensive agents.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders

Neo-Synephrine1934

Priscol1938

phenylephrine1947

hexamethonium1949

Priscoline1949

methonium1950

hydralazine1952

phentolamine1953

methyldopa1954

pentolinium1954

mecamylamine1955

hydrochlorothiazide1958

pempidine1958

guanethidine1959

hydroflumethiazide1959

thiazide1959

pheniprazine1960

pargyline1961

vasodepressor1961

alpha blocker1965

clonidine1969

prazosin1970

timolol1973

the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific

Haarlem oil1885

Salyrgan1924

mersalyl1936

acetazolamide1954

chlorothiazide1957

thiazide1959

triamterene1962

ethacrynic acid1963

frusemide1963

1959 Jrnl. Amer. Med. Assoc. 22 Aug. 2052/2 When the thiazide derivatives are first administered to hypertensive patients being treated with other drugs, it is advisable to continue giving Rauwolfia derivatives.

1961 Lancet 12 Aug. 334/1 The use of guanethidine in combination with one of the thiazide group of diuretics extends the application of these drugs in the management of patients with high blood-pressure.

1974 M. C. Gerald Pharmacol. xxii. 399 When used alone, the thiazides have only weak anti~hypertensive effects.

1980 Brit. Med. Jrnl. 18 Oct. 1053 Vasodilators are used mainly as additional treatment in patients who are not controlled by thiazides and beta-blockers.

This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2022).

单词	thiazide
释义	thiaziden. Brit. /ˈθʌɪəzʌɪd/, U.S. /ˈθaɪəˌzaɪd/ Etymology: < thi- (in thio- comb. form) + az- (in azine n.) + -ide (in oxide n.), elements in the systematic name of the parent compound. Pharmacology. Any of a class of drugs derived from 1,2,4-benzothiadiazine-1,1-dioxide that increase the excretion of sodium and chloride and are used as diuretics and as auxiliary hypotensive agents. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders Neo-Synephrine1934 Priscol1938 phenylephrine1947 hexamethonium1949 Priscoline1949 methonium1950 hydralazine1952 phentolamine1953 methyldopa1954 pentolinium1954 mecamylamine1955 hydrochlorothiazide1958 pempidine1958 guanethidine1959 hydroflumethiazide1959 thiazide1959 pheniprazine1960 pargyline1961 vasodepressor1961 alpha blocker1965 clonidine1969 prazosin1970 timolol1973 the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific Haarlem oil1885 Salyrgan1924 mersalyl1936 acetazolamide1954 chlorothiazide1957 thiazide1959 triamterene1962 ethacrynic acid1963 frusemide1963 1959 Jrnl. Amer. Med. Assoc. 22 Aug. 2052/2 When the thiazide derivatives are first administered to hypertensive patients being treated with other drugs, it is advisable to continue giving Rauwolfia derivatives. 1961 Lancet 12 Aug. 334/1 The use of guanethidine in combination with one of the thiazide group of diuretics extends the application of these drugs in the management of patients with high blood-pressure. 1974 M. C. Gerald Pharmacol. xxii. 399 When used alone, the thiazides have only weak anti~hypertensive effects. 1980 Brit. Med. Jrnl. 18 Oct. 1053 Vasodilators are used mainly as additional treatment in patients who are not controlled by thiazides and beta-blockers. This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2022). < n.1959
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