trometamoln.
/trəʊˈmɛtəmɒl/ Pharmacology.
A white crystalline powder, C4H11NO3, used in solution as an alkalinizing agent; 2-amino-2-hydroxymethylpropane-1,3-diol.
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alkalizate1666
alkalescent1752
antalkali1763
antalkaline1770
trometamol1966
1966 Approved Names (Brit. Pharmacopœia Comm.) 44 Trometamol, 2-amino-2-hydroxymethylpropane-1,3-diol.
1976 Lancet 4 Dec. 1258/1 We do not think that correction of metabolic acidosis by buffers..is the important factor because alkalinisation, by trometamol..for example, has no effect upon cardiac troubles.
1984 Brit. Med. Jrnl. 25 Aug. 460/1 The two tier column assay was carried out..on serum samples diluted 1/5 in trometamol (TRIS) buffer (0.05M trometamol, 0.005M calcium chloride pH 7.5).
This entry has not yet been fully updated (first published 1993; most recently modified version published online June 2018).
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n.1966