tripelennaminen.
/trʌɪpəˈlɛnəmiːn/ Pharmacology.
An antihistamine drug, C16H21N3, given orally as the crystalline hydrochloride or citrate.
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pyribenzamine1946
diphenhydramine1947
tripelennamine1947
mepyramine1949
anti-histaminic1950
meclozine1955
triprolidine1956
antihistamine1957
trimeprazine1959
methapyrilene1974
1947 Jrnl. Amer. Med. Assoc. 31 May 454/2 Granulo~cytopenia is believed not to have been described hitherto among the untoward side effects of tripelennamine hydrochloride, ‘pyribenzamine’ (N.N.R.) (N′-pyridyl-N′-benzyl-N-dimethylethylenediamine hydrochloride), therapy.
1962 F. C. Ferguson Drug Therapy xliv. 346 Recommended agents are promethazine, or Phenergan (if marked sedation is desired), tripelennamine, or Pyribenzamine (for lesser degree of sedation), and phenindamine (Thephorin).
1974 M. C. Gerald Pharmacol. ii. 30 Antihistamines such as tripelennamine (Pyribenzamine) do not cure allergies, but they do prevent the agonist, histamine, from initiating an allergic response.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1947