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单词 trisomy-21
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trisomy-21
ˈtrisomy n. trisomic state; frequently with following numeral denoting the chromosome concerned, as trisomy-21 (associated with Down's syndrome).
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the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromosome > types of chromosome > condition
trisomy1930
monosomy1931
polyteny1942
tetrasomy1961
nullisomy1966
1930 Bibliographia Genetica VI. 15 Further observations..disclosed a high degree of intraspecific variation resulting in polyploidy, trisomy, fragmentation of chromosomes [etc.].
1961 G. Allen et al. in Lancet 8 Apr. 775/2 Several others [of the undersigned] believe that this is an appropriate time to introduce the term ‘trisomy 21 anomaly’ which would include cases of simple trisomy as well as translocations.
1963 Lancet 12 Jan. 114/2 The repeated demonstration of dermatoglyphic abnormalities in the autosomal trisomies..leads us to wonder whether each autosomal trisomy syndrome will prove to be dermatoglyphically distinctive.
1965 H. E. Sutton Introd. Human Genetics v. 37 The condition known as trisomy 21 syndrome or mongolian idiocy (sometimes referred to as Down's syndrome) had long been an enigma.
1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xxxi. 19/1 The relative frequency of trisomy 13–15 in abortuses indicates that it is less compatible with normal intra-uterine development than either trisomy 17–18 or mongolism.
1977 Nature 6 Jan. 65/2 Case 2..showed an excess of α-globin synthesis smaller than expected for functional trisomy of the α-globin genetic region.
1979 Nature 4 Jan. 57/1 Although the patient had no features of the trisomy 21 syndrome, two first-degree cousins of his father had given birth to children with Down's syndrome.
extracted from trisomicadj.n.
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