In gonadectomized female and male animals, 3045 genes were differentially expressed by 1.5-fold change, compared to sham controls.
Telma Quintela, Isabel Gonçalves, Laura C. Carreto, Manuel A. S. Santos, Helena Marcelino,Filipa M. Patriarca, Cecília R. A. Santos 2013, 'Analysis of the Effects of Sex Hormone Background on the Rat Choroid Plexus Transcriptomeby cDNA Microarrays', PLoS ONE10.1371/journal.pone.0060199. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Intact females had better performances than gonadectomized females in solving a learning task in a maze.
Anna Scandurra, Alessandra Alterisio, Anna Di Cosmo, Antonio D'Ambrosio, Biagio D'Aniello 2019, 'Ovariectomy Impairs Socio-Cognitive Functions in Dogs', Animalshttps://www.mdpi.com/2076-2615/9/2/58. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)