an enzyme of the esterase group that catalyses the hydrolysis of sulphate esters
Examples of 'sulfatase' in a sentence
sulfatase
Sulfatase genes had the highest relative abundance below 2 mm.
Mercedes Berlanga, Montserrat Palau, Ricardo Guerrero, Ricardo Guerrero 2017, 'Functional Stability and Community Dynamics during Spring and Autumn Seasons Over3 Years in Camargue Microbial Mats', Frontiers in Microbiologyhttp://journal.frontiersin.org/article/10.3389/fmicb.2017.02619/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Data on expression of sulfatase and sulfotransferases in gynecological diseases arealso reviewed.
Tea eLanisnik Rizner 2016, 'The important roles of steroid sulfatase and sulfotransferases in gynecological diseases',Frontiers in Pharmacologyhttp://journal.frontiersin.org/Journal/10.3389/fphar.2016.00030/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Liver iduronate-2-sulfatase concentration was approximately 10-fold higher than kidney.
Jou-Ku Chung, Eilish Brown, Bob Crooker, Kathleen J. Palmieri, Thomas G. McCauley 2016, 'Biodistribution of Idursulfase Formulated for Intrathecal Use (Idursulfase-IT) inCynomolgus Monkeys after Intrathecal Lumbar Administration', PLOS ONE10.1371/journal.pone.0164765. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, thus far no sulfatase-rich marine anaerobes are known.
Daan M. van Vliet, Susakul Palakawong Na Ayudthaya, Susakul Palakawong Na Ayudthaya,Sally Diop, Laura Villanueva, Alfons J. M. Stams, Alfons J. M. Stams, Irene Sánchez-Andrea 2019, 'Anaerobic Degradation of Sulfated Polysaccharides by Two Novel Kiritimatiellales StrainsIsolated From Black Sea Sediment', Frontiers in Microbiologyhttps://www.frontiersin.org/article/10.3389/fmicb.2019.00253/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Cerebrospinal fluid pharmacokinetic profiles at different doses of iduronate-2-sulfatase were similar and the dose/exposure relationship was proportional.
Hongsheng Xie, Jou-Ku Chung, Mary Ann Mascelli, Thomas G. McCauley 2015, 'Pharmacokinetics and Bioavailability of a Therapeutic Enzyme (Idursulfase) in CynomolgusMonkeys after Intrathecal and Intravenous Administration', PLOS ONE10.1371/journal.pone.0122453. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
After intrathecal administration, movement of iduronate-2-sulfatase from cerebrospinal fluid to serum was observed (systemic bioavailability was 40–83%).
Hongsheng Xie, Jou-Ku Chung, Mary Ann Mascelli, Thomas G. McCauley 2015, 'Pharmacokinetics and Bioavailability of a Therapeutic Enzyme (Idursulfase) in CynomolgusMonkeys after Intrathecal and Intravenous Administration', PLOS ONE10.1371/journal.pone.0122453. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This method facilitates in detection of faint alkyl sulfatase bands which are otherwise difficult to visualize.
Venkatesh Chaturvedi*, Ashok Kumar 2010, 'A Simple Staining Method for Increasing Sensitivity in Detection of Alkyl Sulfatasein Native Polyacrylamide Gels', Journal of Phytologyhttps://updatepublishing.com/journal/index.php/jp/article/view/2142. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Iduronate-2-sulfatase exposure in the cerebrospinal fluid was limited, suggesting intravenous administration provided minimal penetration of the blood–brain barrier.
Hongsheng Xie, Jou-Ku Chung, Mary Ann Mascelli, Thomas G. McCauley 2015, 'Pharmacokinetics and Bioavailability of a Therapeutic Enzyme (Idursulfase) in CynomolgusMonkeys after Intrathecal and Intravenous Administration', PLOS ONE10.1371/journal.pone.0122453. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Both strains encoded a single anaerobic sulfatase-maturating enzyme which could be responsible for post-translational modification of formylglycine-dependent sulfatases.
Daan M. van Vliet, Susakul Palakawong Na Ayudthaya, Susakul Palakawong Na Ayudthaya,Sally Diop, Laura Villanueva, Alfons J. M. Stams, Alfons J. M. Stams, Irene Sánchez-Andrea 2019, 'Anaerobic Degradation of Sulfated Polysaccharides by Two Novel Kiritimatiellales StrainsIsolated From Black Sea Sediment', Frontiers in Microbiologyhttps://www.frontiersin.org/article/10.3389/fmicb.2019.00253/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We developed an activity-based probe 1 for detection of bacterial sulfatase activity through liquid- and solid-phase colony-basedassays.
Hey Young Yoon, Hyung Jun Kim, Soojin Jang, Jong-In Hong 2017, 'Detection of bacterial sulfatase activity through liquid- and solid-phase colony-basedassays', AMB Expresshttp://link.springer.com/article/10.1186/s13568-017-0449-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)