not selective or characterized by indiscriminate selection
Examples of 'unselective' in a sentence
unselective
Autophagy has long been thought to be an essential but unselective bulk degradation pathway.
Christian Behrends, Simone Fulda 2012, 'Receptor Proteins in Selective Autophagy', International Journal of Cell Biologyhttp://dx.doi.org/10.1155/2012/673290. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, hydroxyl radicals follow unselective multi-step pathways, limiting their efficiency in complex environmental matrices.
Monica Brienza, Ioannis A. Katsoyiannis 2017, 'Sulfate Radical Technologies as Tertiary Treatment for the Removal of Emerging Contaminantsfrom Wastewater', Sustainabilityhttps://www.mdpi.com/2071-1050/9/9/1604. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, due to the rather unselective nature of the electrochemical depolymerization, overoxidation of the generated products occurs.
Serafin Stiefel, Jonas Lölsberg, Lukas Kipshagen, Robin Möller-Gulland, Matthias Wessling 2015, 'Controlled depolymerization of lignin in an electrochemical membrane reactor', Electrochemistry Communicationshttp://www.sciencedirect.com/science/article/pii/S1388248115002726. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, while observational studies often include unselective patient populations, many do not adequately address other limitations of pre-approval trials.
Dobre Daniela, de Zeeuw Dick, Haaijer-Ruskamp Flora M, Hakobyan Liana, Denig Petra 2011, 'A review of methods used in assessing non-serious adverse drug events in observationalstudies among type 2 diabetes mellitus patients', Health and Quality of Life Outcomeshttp://www.hqlo.com/content/9/1/83. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These unselective methods decompose lignin into many products that may not be energetically or chemically valuable, or even biologically inhibitory.
Walter Den, Virender K. Sharma, Mengshan Lee, Govind Nadadur, Rajender S. Varma 2018, 'Lignocellulosic Biomass Transformations via Greener Oxidative Pretreatment Processes:Access to Energy and Value-Added Chemicals', Frontiers in Chemistryhttp://journal.frontiersin.org/article/10.3389/fchem.2018.00141/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Overall, the dual antagonists tested here tend to be rather unselective under non-equilibrium conditions and reachequilibrium very slowly.
Gabrielle Elizabeth Callander, Gabrielle Elizabeth Callander, Morenike eOlorunda,Dominique eMonna, Edi eSchuepbach, Daniel eLangenegger, Claudia eBetschart, SamueleHintermann, Dirk eBehnke, Simona eCotesta, Markus eFendt, Grit eLaue, Silvio eOfner,Emmanuelle eBriard, Christine E. Gee, Daniel eHoyer, Laura H. Jacobson, Daniel eHoyer,Daniel eHoyer 2013, 'Kinetic properties of 'dual' orexin receptor antagonists at OX1R and OX2Rorexin receptors.', Frontiers in Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fnins.2013.00230/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In fact, recent studies have yielded data that suggest that unselective supplementation of selenium may, indeed, be harmful.
Joseph Loscalzo, Jacob Joseph 2013, 'Selenistasis: Epistatic Effects of Selenium on Cardiovascular Phenotype', Nutrientshttp://www.mdpi.com/2072-6643/5/2/340. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)