Hürthle cell tumor


Hürthle cell tumor

 [hērt´lĕ] a new growth of the thyroid gland composed wholly or predominantly of Askanazy cells (Hürthle cells) having abundant granular, eosinophilic cytoplasm. Such tumors are usually benign (adenoma" >Hürthle cell adenoma) but on occasion may be locally invasive or may rarely metastasize (carcinoma" >Hürthle cell carcinoma).

Hürth·le cell tu·mor

(hērt'lĕ sel tū'mŏr) A neoplasm of the thyroid gland composed of polyhedral acidophilic cells, thought by some to be oncocytes; it may be benign or malignant, the behavior of the latter depending on the general microscopic pattern, whether follicular, papillary, or undifferentiated.
See also: Hürthle cell adenoma
Synonym(s): Hürthle cell carcinoma.

Hürthle,

Karl W., German histologist, 1860-1945. Hürthle cell - a large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria, e.g., in Hashimoto disease. Synonym(s): Askanazy cellHürthle cell adenoma - a follicular adenoma of the thyroid in which the epithelium has undergone metaplasia into Hürthle cells.Hürthle cell carcinoma - Synonym(s): Hürthle cell tumorHürthle cell tumor - neoplasm of the thyroid gland. Synonym(s): Hürthle cell carcinoma