indirect Coombs test

in·di·rect Coombs test

(kūmz), Avoid the incorrect forms Coomb and Coomb's.a test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in the donor cells; after a washing with saline, Coombs antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes.

Coombs in·di·rect test

(kūmz in'dĭr-ekt' test) Laboratory test using serum that contains an antibody that may be used for erythrocyte typing; positive (i.e., abnormal) finding in isoimmunization from previous transfusions of incorrect cross-matching.
See: Coombs test
Synonym(s): indirect Coombs test.

Coombs,

Robin R.A., English veterinarian and immunologist, 1921–. Coombs serum - serum from a rabbit or other animal previously immunized with purified human globulin to prepare antibodies directed against IgG and complement. Synonym(s): antihuman globulinCoombs test - a test for antibodies, the so-called antihuman globulin test, using either the direct or indirect Coombs tests. Synonym(s): antiglobulin testdirect Coombs test - a test for detecting sensitized erythrocytes in erythroblastosis fetalis and in cases of acquired immune hemolytic anemia.Gell and Coombs reaction - see under Gellindirect Coombs test - a test routinely performed in cross-matching blood or in the investigation of transfusion reaction.

单词	indirect coombs test
释义	indirect Coombs test indirect Coombs test [‚in·də′rekt ′kümz ‚test] (immunology) Rh blocking test indirect Coombs test in·di·rect Coombs test (kūmz), Avoid the incorrect forms Coomb and Coomb's.a test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in the donor cells; after a washing with saline, Coombs antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes. Coombs in·di·rect test (kūmz in'dĭr-ekt' test) Laboratory test using serum that contains an antibody that may be used for erythrocyte typing; positive (i.e., abnormal) finding in isoimmunization from previous transfusions of incorrect cross-matching. See: Coombs test Synonym(s): indirect Coombs test. Coombs, Robin R.A., English veterinarian and immunologist, 1921–. Coombs serum - serum from a rabbit or other animal previously immunized with purified human globulin to prepare antibodies directed against IgG and complement. Synonym(s): antihuman globulinCoombs test - a test for antibodies, the so-called antihuman globulin test, using either the direct or indirect Coombs tests. Synonym(s): antiglobulin testdirect Coombs test - a test for detecting sensitized erythrocytes in erythroblastosis fetalis and in cases of acquired immune hemolytic anemia.Gell and Coombs reaction - see under Gellindirect Coombs test - a test routinely performed in cross-matching blood or in the investigation of transfusion reaction.
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