| 释义 |
interleukin-1
in·ter·leu·kin-1 I0189125 (ĭn′tər-lo͞o′kĭn-wŭn′)n. Any of a family of cytokines that are released by macrophages and other cells and stimulate the inflammatory response.interleukin-1
interleukin-1[‚in·tər¦lük·ən ′wən] (immunology) A cytokine produced by macrophages, endothelial cells, lymphocytes, and epidermal cells that plays roles in the inflammatory process and in the immune response. Abbreviated IL-1. interleukin-1
in·ter·leu·kin-·1 (in'tĕr-lū'kin), A cytokine, derived primarily from mononuclear phagocytes, that enhances the proliferation of T-helper cells and the growth and differentiation of B cells. Il-1 induces the release of Il-2. When secreted in larger quantities, IL-1 is a mediator of inflammation, entering the bloodstream and causing fever, inducing synthesis of acute phase proteins, and initiating metabolic wasting. There are two distinct forms of IL-1:, α and β, both of which perform the same functions but represent different proteins.interleukin-1 (ĭn′tər-lo͞o′kĭn-wŭn′)n. Any of a family of cytokines that are released by macrophages and other cells and stimulate the inflammatory response.in·ter·leu·kin-1 (in'tĕr-lū'kin) A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells. interleukin-1 A powerful polypeptide hormone produced by MACROPHAGES and fibroblasts that acts on LYMPHOCYTES to increase their ability to respond to ANTIGENS. Interleukin-1 is also responsible for resetting the temperature regulating mechanism at a higher level and thus causing fever, for the induction of the release of ACUTE PHASE PROTEINS, and for promoting the absorption of bone by OSTEOCLASTS.in·ter·leu·kin-1 (in'tĕr-lū'kin) A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells. ThesaurusSeeinterleukin |