isocitrate dehydrogenase


i·so·cit·rate de·hy·dro·gen·ase

one of two enzymes that catalyze the conversion of threo-ds-isocitrate, the product of the action of both aconitase and isocitrate lyase, to α-ketoglutarate (2-oxoglutarate) and CO2; one of the isozymes uses NAD+ (participating in the tricarboxylic acid cycle), whereas the other uses NADP+. Synonym(s): isocitric acid dehydrogenase, oxalosuccinic carboxylase

i·so·ci·trate de·hy·dro·gen·ase

(ī'sō-sit'rāt dē'hī-droj'ĕn-ās) One of two enzymes that catalyze the conversion of threo-ds-isocitrate to α-ketoglutarate (2-oxoglutarate) and CO2.

isocitrate dehydrogenase

(ī″sō-cĭt′rāt dē″hī-drŏj′ĕn-ās) An enzyme that catalyzes the conversion of isocitric acid to α-ketoglutaric acid.