juvenile myelomonocytic leukaemia

juvenile myelomonocytic leukaemia

A paediatric myelodysplastic syndrome (OMIM:607785) which comprises approximately 30% of childhood cases of myelodysplastic syndrome and 2% of leukaemia.
Molecular pathology
Germline mutations of NF1 account for the association of JMML with type-1 neurofibromatosis.