adenomatous polyposis coli

familial adenomatous polyposis (FAP),

[MIM*175100] polyposis that usually begins in childhood; polyps increase in number, causing symptoms of chronic colitis; pigmented retinal lesions are frequently found; carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance, caused by mutation in the adenomatous polyposis coli gene (APC) on 5q. In Gardner syndrome, which is allelic to FAP, there are extracolonic changes (desmoid tumors, osteomas, jaw cysts). Synonym(s): adenomatous polyposis coli, familial polyposis coli, multiple intestinal polyposis (1)

APC

Abbreviation for:
activated protein C (see there)
adenomatous polyposis coli (see there)
aerobic plate count (microbiology)
air pollution control
allophycocyanin
ammonium perchlorate
amyloid pack core
antigen-presenting cell (see there)
antiphlogistic-corticoid (obsolete)
aperature current
apneustic centre (neuroanatomy)
arterial premature contraction
aspirin, phenacetin, caffeine
Association of Pathology Chairmen
Association of Professors of Cardiology
atrial premature contraction (see there)
Adenoma Prevention with Celecoxib (clinical trials)
ambulatory payment classification (see there) (Managed care)
APC gene (molecular medicine)
APC protein (molecular medicine)
Genetics
A gene on chromosome 5q21-q22 that encodes a tumour-suppressor protein which acts as an antagonist of the Wnt signalling pathway. APC is also involved in cell migration and adhesion, transcriptional activation, and apoptosis.
Molecular Pathology
APC mutations cause familial adenomatous polyposis.

adenomatous polyposis coli

Familial adenomatous polyposis, see there. See APC gene, APC protein.

fa·mi·li·al ad·e·nom·a·tous pol·y·po·sis

(FAP) (fă-mil'ē-ăl ad'ĕ-nō'mă-tŭs pol'i-pō'sis) Polyposis of the colon that usually begins in childhood; polyps increase in number, causing symptoms of chronic colitis; pigmented retinal lesions are frequently found; carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance, caused by mutation in the adenomatous polyposis coli gene (APC) on 5q. In Gardner syndrome, which is allelic to FAP, there are extracolonic changes (desmoid tumors, osteomas, jaw cysts).
Synonym(s): adenomatous polyposis coli, familial polyposis coli.

单词	adenomatous polyposis coli
释义	DictionarySeeAPC adenomatous polyposis coli familial adenomatous polyposis (FAP), [MIM175100] polyposis that usually begins in childhood; polyps increase in number, causing symptoms of chronic colitis; pigmented retinal lesions are frequently found; carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance, caused by mutation in the adenomatous polyposis coli gene (APC) on 5q. In Gardner syndrome, which is allelic to FAP, there are extracolonic changes (desmoid tumors, osteomas, jaw cysts). Synonym(s): adenomatous polyposis coli, familial polyposis coli, multiple intestinal polyposis (1) APC Abbreviation for: activated protein C (see there) adenomatous polyposis coli (see there) aerobic plate count (microbiology) air pollution control allophycocyanin ammonium perchlorate amyloid pack core antigen-presenting cell (see there) antiphlogistic-corticoid (obsolete) aperature current apneustic centre (neuroanatomy) arterial premature contraction aspirin, phenacetin, caffeine Association of Pathology Chairmen Association of Professors of Cardiology atrial premature contraction (see there) Adenoma Prevention with Celecoxib (clinical trials) ambulatory payment classification (see there) (Managed care) APC gene (molecular medicine) APC protein (molecular medicine) Genetics A gene on chromosome 5q21-q22 that encodes a tumour-suppressor protein which acts as an antagonist of the Wnt signalling pathway. APC is also involved in cell migration and adhesion, transcriptional activation, and apoptosis. Molecular Pathology APC mutations cause familial adenomatous polyposis. adenomatous polyposis coli Familial adenomatous polyposis, see there. See APC gene, APC protein. fa·mi·li·al ad·e·nom·a·tous pol·y·po·sis (FAP)* (fă-mil'ē-ăl ad'ĕ-nō'mă-tŭs pol'i-pō'sis) Polyposis of the colon that usually begins in childhood; polyps increase in number, causing symptoms of chronic colitis; pigmented retinal lesions are frequently found; carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance, caused by mutation in the adenomatous polyposis coli gene (APC) on 5q. In Gardner syndrome, which is allelic to FAP, there are extracolonic changes (desmoid tumors, osteomas, jaw cysts). Synonym(s): adenomatous polyposis coli, familial polyposis coli. AcronymsSeeactivated protein c
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